Monday, December 23, 2013

EDITAS revolution


A startup founded by five American scientists, EDITAS Medicine,  proposes to sell human gene therapy. We are fast reaching a time when one-gene hereditary diseases will be curable, and then, the genetic load problem will be solved. Human evolution actuated by the environment is a closed chapter. Human Biological Differences are now a genetic disease of the past, easily cured in the near future. Skin color, tendency to violence, etc. will last one generation or less. We (humanity) are now designing humans.

24 comments:

Anonymous said...

Already there are deaf parents who refuse to allow their deaf children to receive operations that will restore them to hearing - to do so would alienate them from "deaf culture". What makes you think that parents will want their children to be cured of Negritude? Barack Obama sought it out.

K

B said...

They will keep their negritude while getting rid of any genetic disadvantages. Imagine, a black population with the current preferential treatment but an average IQ of 100.

J said...

No way, gentlemen. Even today African people try to straighten their hair, paint it yellow, and they buy expensive creams to whiten their complexion. Only the very poor or those not covered by Obamacare will been visibly different. It may take a few more years, but not far away the day when the world will celebrate the first "Black" or formerly black Nobel Prize winner in Physics.

We, Jews, will have lost our advantage in intelligence and scholarship. We will be like everybody else, just as we prayed for.

Universal brotherhood will reign, since why wage war for a small difference in genes, that are proteins and sugars arranged in this or that order. That can easily knocked out and replaced by a synthetic one.

Happily I will not be here to live those times.

J said...

Correction: instead of proteins DNA is built with aminoacids. The same stupid stuff.

spagetiMeatball said...

Now, now, don't get ahead of yourself.

spagetiMeatball said...

Yeah, but then in your future there will be other problems, like robots outdoing humans in the nobel prizes.

J said...

That's why I am happy to leave some problems to solve by future generations. I dont want to give them all in a silver tray.

Anonymous said...

Already American blacks reject readily available measures such as striving for academic achievement. This is called "acting white" and is looked down upon. Americans have always been suspicious of intelligence - the American ideal is the athlete, not the scholar.

K

spagetiMeatball said...

Whose ideal is the scholar?

J said...

It is definitely the Jewish ideal.

I think that K is exaggerating American anti-intellectual mood, but then, he is there and I am in the Middle East.

J said...

What K is saying that American Blacks will not go for gene therapy even if freely available, because they are happy as they are.

But th Chinese are most interested in making better babies, and they are many.

Anyway, why should I worry about the future. Let the young and yet-to-be-born to deal with the reality of their times, as I did with with mine.

spagetiMeatball said...

We are still far away from developing gene therapy for complex traits like intelligence. Maybe skin color will be sooner because there is a lot of famous genes of large effect like SLC45A2 (which I have) that is responsible for something like 20% of skin color variation in Europe, and 68% in South asia.
Easiest thing to do is investigate the chemical reactions in the melanocytes of people with SLC45A2 and compare it to the same in people without. East asians and Africans don't have this gene.

If some intelligence-boosting technology does appear I am sure the chinese will apply to their math olympiad team, by force if necessary.

Other dictarships may follow suit: Iran, north korea, etc.

spagetiMeatball said...

Eventually humans will become massive floating heads with stunted, scrawny arms and legs attached.

spagetiMeatball said...

Btw, I did a google search of your forum for "Leo Gleser", israeli-argentinean weapons trader, and security expert extraordinaire, and found no mention.


Pour que non?

Anonymous said...

Spageti is right. Gene therapy for complext traits is not near at hand, partly because the genes themselves have not been identified, nor the specific effects of different mutations/polymorphisms in those genes. There is also the issue of the recently discovered "second code" in DNA that, in addition to environmental effects, would further modify any edits. Then there is the issue of how well any gene therapy would work in an adult organism compared to an embryo. If the protein product needs to be expressed in cells throughout the body, that's not an easy fix to make in an adult.

Anonymous said...

The easiest fix would be thru conventional breeding techniques which are already well understood. Since fathers are rarely around, black females could be impregnated with the sperm of high intelligence black men like Obama's father (they would not want mulatto babies in most cases). But you can see that in the current environment (in which any mention of intelligence is racis') such a plan could never get off the ground, no less some high tech genetic engineering scheme.

J is imagining a science fiction future but the real future (at least in America) will be a lot more third worldish than science fictiony - more Soylent Green than Jetsons. Already in the California public schools Hispanics outnumber whites (who are only 26%) two to one (and the Hispanics are not interested in academics).

Basically what happened in the Caribbean is going to happen in the US and Europe. Whites (after killing off the native inhabitants) imported blacks to be their slaves but in the end they were vastly outnumbered and the Columbian discovery turned out to be a method for repopulating the Americas with Africans.


K

J said...

Few know that was exactly what happened in South Africa too.

B said...

>they would not want mulatto babies in most cases

You must not have much experience with black women. "My baby got dat good hurr" etc.

Anonymous said...

"instead of proteins DNA is built with aminoacids"

Sorry to be pedantic, but DNA is built of nucleotides which code for the amino acid sequence in the proteins, via transcription and translation.

And yes, when the ability to genetically engineer intelligence does become available, it will be ruthlessly forced on blacks by the authoritarian left, with the explicit intention of making them smarter than whites.

Anon.

Anonymous said...

Cochran hinted a while ago that BGI was having trouble finding genes that influence intelligence. For all we know, there are even more genetic loci for intelligence than expected, most with such tiny effect that they are difficult to detect at all. The more genes and polymorphisms involved, the harder intelligence would be to fix. It will probably be at least a few more decades until this all gets worked out. Manipulating complex traits may require working with embryos, implying a further couple of decades to wait until the subjects are adults.

Anonymous said...

Cochran hinted a while ago that BGI was having trouble finding genes that influence intelligence. For all we know, there are even more genetic loci for intelligence than expected, most with such tiny effect that they are difficult to detect at all.

Rietveld's study found intelligence genes (2% of educational outcome variance).

Shouldn't BGI's brute force genome sweeps do at least as well?

http://www.sciencemag.org/content/early/2013/05/29/science.1235488.abstract

Anonymous said...

2% is effectively worthless. You could get a much greater than 2% improvement just with small doses of amphetamines to increase attention. This is already being done for those diagnosed with "ADD" but in fact such medications work for everyone and the Chinese will surely (probably already are) apply them to students at the top end of the spectrum as well.



K

Anonymous said...

I'm not sure that 2% of the variation necessarily translates into a 2% improvement.

A non.

Anonymous said...

If Cochran is right that the Ashkenazi population's deleterious mutations are the source of Ashkenazi intelligence, wouldn't gene therapy be harmful to Ashkenazi intelligence? Editing an Ashkenazi's single mutant Tay-Sachs allele and idiopathic torsion dystonia allele might make him dumber.